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产品目录

重组SARS-CoV-2解旋酶(His标签)图片
产品货号:
JN2072
中文名称:
重组SARS-CoV-2解旋酶(His标签)
英文名称:
Recombinant SARS-CoV-2 Helicase (C-6His tag)
产品规格:
10μg|50μg
发货周期:
1~3天
产品价格:
询价
本制品由E.coli表达系统制备,目的基因编码表达SARS-CoV-2 Helicase(Ala1-Gln601),C端包含一个6*His标签。

Accession#:YP_009725308.1
蛋白别称:SARS-CoV-2 NSP13
贮存液:PBS,10% Glycerol,pH7.4,0.2μm过滤
分子量:70kDa
纯度:>90%(还原SDS-PAGE)
保存条件:-20℃,可稳定保存6个月,应避免反复冻融。

背景资料:
The non—structural protein 13 (nsp13) of SARS—CoV 2 is a helicase that separates double—stranded RNA or DNA with a 5'—3' polarity,using the energy of nucleotide hydrolysis.A basic biochemical characterization of nsp13 demonstrated that it can unwind both doublestranded DNA and RNA in a 5’-3’ direction,and it can hydrolyze all deoxyribonucleotide and ribonucleotide triphosphates.Helicases are motor proteins that utilize the energy derived from nucleotide hydrolysisto unwind double-stranded nucleic acids into two single-stranded nucleic acids.Initially,helicases were only thought to be molecular engines that unwind nucleic acids during replication,recombination,and DNA repair.Recent studies have shown that they are also involved in other biological processes,including displacement of proteins from nucleic acid,movement of Holliday junctions,chromatin remodeling,catalysis of nucleic acid conformational changes,several aspects of RNA metabolism,including transcription,mRNA splicing,mRNA export,translation,RNA stability and mitochondrial gene expression.Some human diseases,including Bloom’s syndrome,Werner’s syndrome,and Xeroderma Pigmentosum have been associated with defects in helicase function.
相关搜索:重组SARS-CoV-2解旋酶(His标签)重组SARS-CoV-2 NSP13重组新型冠状病毒解螺旋酶重组新型冠状病毒Helicase重组SARS-CoV-2非结构蛋白13重组新冠病毒非结构蛋白13Recombinant SARS-CoV-2 Helicase (C-6His tag)
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